AustralieFrV1, Main, Exploration, bibRecord, 001D67

Heterologous vaccine effects.

Identifieur interne : 001D67 ( Main/Exploration ); précédent : 001D66; suivant : 001D68

Heterologous vaccine effects.

Auteurs : Mitra Saadatian-Elahi [France] ; Peter Aaby [Guinée-Bissau] ; Frank Shann [Australie] ; Mihai G. Netea [Pays-Bas] ; Ofer Levy [États-Unis] ; Jacques Louis [France] ; Valentina Picot [France] ; Michael Greenberg [États-Unis] ; William Warren [États-Unis]

Source :

Vaccine [ 1873-2518 ] ; 2016.

RBID : pubmed:27312214

Descripteurs français

KwdFr :
- Congrès comme sujet, France, Humains, Immunité hétérologue, Immunité innée, Mémoire immunologique, Vaccins atténués (immunologie), Vaccins inactivés (immunologie).
MESH :
- immunologie : Vaccins atténués, Vaccins inactivés.
- Congrès comme sujet, France, Humains, Immunité hétérologue, Immunité innée, Mémoire immunologique.

English descriptors

KwdEn :
- Congresses as Topic, France, Humans, Immunity, Heterologous, Immunity, Innate, Immunologic Memory, Vaccines, Attenuated (immunology), Vaccines, Inactivated (immunology).
MESH :
- chemical , immunology : Vaccines, Attenuated, Vaccines, Inactivated.
- Congresses as Topic, France, Humans, Immunity, Heterologous, Immunity, Innate, Immunologic Memory.

Abstract

The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important biological process by a growing group of immunologists and epidemiologists. Much remain to be learned about the extent and underlying mechanisms for these effects. The conference "Off-target effects of vaccination" held in Annecy-France (June 8-10 2015) intended to take a holistic approach drawing from the fields of immunology, systems biology, epidemiology, bioinformatics, public health and regulatory science to address fundamental questions of immunological mechanisms, as well as translational questions about vaccines NSEs. NSE observations were examined using case-studies on live attenuated vaccines and non-live vaccines followed by discussion of studies of possible biological mechanisms. Some possible pathways forward in the study of vaccines NSE were identified and discussed by the expert group.

DOI: 10.1016/j.vaccine.2016.06.020
PubMed: 27312214

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heterologous vaccine effects.</title>
<author><name sortKey="Saadatian Elahi, Mitra" sort="Saadatian Elahi, Mitra" uniqKey="Saadatian Elahi M" first="Mitra" last="Saadatian-Elahi">Mitra Saadatian-Elahi</name>
<affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Groupement Hospitalier Edouard Herriot, 5 Place d'Arsonval, 69437 Lyon cedex 03, France. Electronic address: mitra.elahi@chu-lyon.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Hospices Civils de Lyon, Groupement Hospitalier Edouard Herriot, 5 Place d'Arsonval, 69437 Lyon cedex 03</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Aaby, Peter" sort="Aaby, Peter" uniqKey="Aaby P" first="Peter" last="Aaby">Peter Aaby</name>
<affiliation wicri:level="1"><nlm:affiliation>Bandim Health Project, INDEPTH Network, CP861 Bissau, Guinea-Bissau.</nlm:affiliation>
<country xml:lang="fr">Guinée-Bissau</country>
<wicri:regionArea>Bandim Health Project, INDEPTH Network, CP861 Bissau</wicri:regionArea>
<wicri:noRegion>CP861 Bissau</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shann, Frank" sort="Shann, Frank" uniqKey="Shann F" first="Frank" last="Shann">Frank Shann</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pediatrics, University of Melbourne, Victoria 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Pediatrics, University of Melbourne, Victoria 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Netea, Mihai G" sort="Netea, Mihai G" uniqKey="Netea M" first="Mihai G" last="Netea">Mihai G. Netea</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen</wicri:regionArea>
<placeName><settlement type="city">Nimègue</settlement>
<region type="province" nuts="2">Gueldre</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levy, Ofer" sort="Levy, Ofer" uniqKey="Levy O" first="Ofer" last="Levy">Ofer Levy</name>
<affiliation wicri:level="2"><nlm:affiliation>Precision Vaccines Program, Boston Children's Hospital & Havard Medical School, Boston, MA 02115, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Precision Vaccines Program, Boston Children's Hospital & Havard Medical School, Boston, MA 02115</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Louis, Jacques" sort="Louis, Jacques" uniqKey="Louis J" first="Jacques" last="Louis">Jacques Louis</name>
<affiliation wicri:level="3"><nlm:affiliation>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Picot, Valentina" sort="Picot, Valentina" uniqKey="Picot V" first="Valentina" last="Picot">Valentina Picot</name>
<affiliation wicri:level="3"><nlm:affiliation>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Greenberg, Michael" sort="Greenberg, Michael" uniqKey="Greenberg M" first="Michael" last="Greenberg">Michael Greenberg</name>
<affiliation wicri:level="2"><nlm:affiliation>Sanofi Pasteur, San Francisco, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Sanofi Pasteur, San Francisco, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Warren, William" sort="Warren, William" uniqKey="Warren W" first="William" last="Warren">William Warren</name>
<affiliation wicri:level="2"><nlm:affiliation>Sanofi Pasteur, Orlando, FL 32826, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Sanofi Pasteur, Orlando, FL 32826</wicri:regionArea>
<placeName><region type="state">Floride</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:27312214</idno>
<idno type="pmid">27312214</idno>
<idno type="doi">10.1016/j.vaccine.2016.06.020</idno>
<idno type="wicri:Area/PubMed/Corpus">001B83</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001B83</idno>
<idno type="wicri:Area/PubMed/Curation">001B59</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001B59</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001B59</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001B59</idno>
<idno type="wicri:Area/Ncbi/Merge">003720</idno>
<idno type="wicri:Area/Ncbi/Curation">003720</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003720</idno>
<idno type="wicri:Area/Main/Merge">001D64</idno>
<idno type="wicri:Area/Main/Curation">001D67</idno>
<idno type="wicri:Area/Main/Exploration">001D67</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Heterologous vaccine effects.</title>
<author><name sortKey="Saadatian Elahi, Mitra" sort="Saadatian Elahi, Mitra" uniqKey="Saadatian Elahi M" first="Mitra" last="Saadatian-Elahi">Mitra Saadatian-Elahi</name>
<affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Groupement Hospitalier Edouard Herriot, 5 Place d'Arsonval, 69437 Lyon cedex 03, France. Electronic address: mitra.elahi@chu-lyon.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Hospices Civils de Lyon, Groupement Hospitalier Edouard Herriot, 5 Place d'Arsonval, 69437 Lyon cedex 03</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Aaby, Peter" sort="Aaby, Peter" uniqKey="Aaby P" first="Peter" last="Aaby">Peter Aaby</name>
<affiliation wicri:level="1"><nlm:affiliation>Bandim Health Project, INDEPTH Network, CP861 Bissau, Guinea-Bissau.</nlm:affiliation>
<country xml:lang="fr">Guinée-Bissau</country>
<wicri:regionArea>Bandim Health Project, INDEPTH Network, CP861 Bissau</wicri:regionArea>
<wicri:noRegion>CP861 Bissau</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shann, Frank" sort="Shann, Frank" uniqKey="Shann F" first="Frank" last="Shann">Frank Shann</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pediatrics, University of Melbourne, Victoria 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Pediatrics, University of Melbourne, Victoria 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Netea, Mihai G" sort="Netea, Mihai G" uniqKey="Netea M" first="Mihai G" last="Netea">Mihai G. Netea</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen</wicri:regionArea>
<placeName><settlement type="city">Nimègue</settlement>
<region type="province" nuts="2">Gueldre</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levy, Ofer" sort="Levy, Ofer" uniqKey="Levy O" first="Ofer" last="Levy">Ofer Levy</name>
<affiliation wicri:level="2"><nlm:affiliation>Precision Vaccines Program, Boston Children's Hospital & Havard Medical School, Boston, MA 02115, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Precision Vaccines Program, Boston Children's Hospital & Havard Medical School, Boston, MA 02115</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Louis, Jacques" sort="Louis, Jacques" uniqKey="Louis J" first="Jacques" last="Louis">Jacques Louis</name>
<affiliation wicri:level="3"><nlm:affiliation>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Picot, Valentina" sort="Picot, Valentina" uniqKey="Picot V" first="Valentina" last="Picot">Valentina Picot</name>
<affiliation wicri:level="3"><nlm:affiliation>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fondation Mérieux, 17 rue Bourgelat, 69002 Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Greenberg, Michael" sort="Greenberg, Michael" uniqKey="Greenberg M" first="Michael" last="Greenberg">Michael Greenberg</name>
<affiliation wicri:level="2"><nlm:affiliation>Sanofi Pasteur, San Francisco, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Sanofi Pasteur, San Francisco, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Warren, William" sort="Warren, William" uniqKey="Warren W" first="William" last="Warren">William Warren</name>
<affiliation wicri:level="2"><nlm:affiliation>Sanofi Pasteur, Orlando, FL 32826, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Sanofi Pasteur, Orlando, FL 32826</wicri:regionArea>
<placeName><region type="state">Floride</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Vaccine</title>
<idno type="eISSN">1873-2518</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Congresses as Topic</term>
<term>France</term>
<term>Humans</term>
<term>Immunity, Heterologous</term>
<term>Immunity, Innate</term>
<term>Immunologic Memory</term>
<term>Vaccines, Attenuated (immunology)</term>
<term>Vaccines, Inactivated (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Congrès comme sujet</term>
<term>France</term>
<term>Humains</term>
<term>Immunité hétérologue</term>
<term>Immunité innée</term>
<term>Mémoire immunologique</term>
<term>Vaccins atténués (immunologie)</term>
<term>Vaccins inactivés (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Vaccines, Attenuated</term>
<term>Vaccines, Inactivated</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Vaccins atténués</term>
<term>Vaccins inactivés</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Congresses as Topic</term>
<term>France</term>
<term>Humans</term>
<term>Immunity, Heterologous</term>
<term>Immunity, Innate</term>
<term>Immunologic Memory</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Congrès comme sujet</term>
<term>France</term>
<term>Humains</term>
<term>Immunité hétérologue</term>
<term>Immunité innée</term>
<term>Mémoire immunologique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important biological process by a growing group of immunologists and epidemiologists. Much remain to be learned about the extent and underlying mechanisms for these effects. The conference "Off-target effects of vaccination" held in Annecy-France (June 8-10 2015) intended to take a holistic approach drawing from the fields of immunology, systems biology, epidemiology, bioinformatics, public health and regulatory science to address fundamental questions of immunological mechanisms, as well as translational questions about vaccines NSEs. NSE observations were examined using case-studies on live attenuated vaccines and non-live vaccines followed by discussion of studies of possible biological mechanisms. Some possible pathways forward in the study of vaccines NSE were identified and discussed by the expert group.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
<li>Guinée-Bissau</li>
<li>Pays-Bas</li>
<li>États-Unis</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Californie</li>
<li>Floride</li>
<li>Gueldre</li>
<li>Massachusetts</li>
<li>Rhône-Alpes</li>
<li>Victoria (État)</li>
</region>
<settlement><li>Lyon</li>
<li>Melbourne</li>
<li>Nimègue</li>
</settlement>
<orgName><li>Université de Melbourne</li>
</orgName>
</list>
<tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Saadatian Elahi, Mitra" sort="Saadatian Elahi, Mitra" uniqKey="Saadatian Elahi M" first="Mitra" last="Saadatian-Elahi">Mitra Saadatian-Elahi</name>
</region>
<name sortKey="Louis, Jacques" sort="Louis, Jacques" uniqKey="Louis J" first="Jacques" last="Louis">Jacques Louis</name>
<name sortKey="Picot, Valentina" sort="Picot, Valentina" uniqKey="Picot V" first="Valentina" last="Picot">Valentina Picot</name>
</country>
<country name="Guinée-Bissau"><noRegion><name sortKey="Aaby, Peter" sort="Aaby, Peter" uniqKey="Aaby P" first="Peter" last="Aaby">Peter Aaby</name>
</noRegion>
</country>
<country name="Australie"><region name="Victoria (État)"><name sortKey="Shann, Frank" sort="Shann, Frank" uniqKey="Shann F" first="Frank" last="Shann">Frank Shann</name>
</region>
</country>
<country name="Pays-Bas"><region name="Gueldre"><name sortKey="Netea, Mihai G" sort="Netea, Mihai G" uniqKey="Netea M" first="Mihai G" last="Netea">Mihai G. Netea</name>
</region>
</country>
<country name="États-Unis"><region name="Massachusetts"><name sortKey="Levy, Ofer" sort="Levy, Ofer" uniqKey="Levy O" first="Ofer" last="Levy">Ofer Levy</name>
</region>
<name sortKey="Greenberg, Michael" sort="Greenberg, Michael" uniqKey="Greenberg M" first="Michael" last="Greenberg">Michael Greenberg</name>
<name sortKey="Warren, William" sort="Warren, William" uniqKey="Warren W" first="William" last="Warren">William Warren</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D67 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001D67 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:27312214
   |texte=   Heterologous vaccine effects.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27312214" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Heterologous vaccine effects.

Heterologous vaccine effects.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.